You’ve probably heard a lot about endometriosis, a reproductive health condition that can cause incredibly debilitating pelvic pain. Some experts believe it’s caused by endometrial tissue—which makes up the uterine lining—migrating from the uterus to other organs. Others say that the tissue is not made up of endometrial cells, but something similar that can create its own estrogen. Either way, these cells cause inflammation that can affect the lower back. Sciatica pain radiates from the lower back toward the feet. Sciatica may feel like a cramp in the leg, burning, tingling, pins and needles, or numbness. Learn about sciatica causes, exercises, treatment and pain relief. Heart Disease In lumbar flexion, the highest strains are recorded within the interspinous and supraspinous ligaments, followed by the intracapsular ligaments and the ligamentum flavum. In lumbar extension, the anterior longitudinal ligament experiences the highest strain. 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